Publications

Papers (original articles, reviews and preprints) published by our core-funded students 

‘Wastewater surveillance of antimicrobial resistance in human populations: A systematic review’
Kevin Chau, Leanne Barker, Natalie Sims, Barbara Kasprzyk-Hordern, Eric Budgell, Elinor Harriss, Derrick Crook, Daniel Read, Sarah Walker and Nicole Stoesser
Preprints (13 October 2020) https://doi.org/10.20944/preprints202010.0267.v1

‘Hybrid assembly of an agricultural slurry virome reveals a diverse and stable community with the potential to alter the metabolism and virulence of veterinary pathogens’
Ryan Cook, Steven Hooton, Urmi Trivedi, Liz King, Christine Dodd, Jon Hobman, Dov J. Stekel, Michael Jones and Andrew D. Millard. 
bioRxiv (8 October 2020) https://doi.org/10.1101/2020.10.08.329714

‘Proteomics identifies a type 1 IFN, prothrombotic hyperinflammatory circulating COVID-19 neutrophil signature distinct from non-COVID-19 ARDS’
Leila Rayes, Manuel Alejandro Sanchez-Garcia, Tyler Morrison, Andrew JM Howden, Emily R Watta, Simone Arienti, Pranvera Sadiku, Patricia Coelho, Ananda S Mirchandani, David Hope, Sarah K Clark, Jo Singleton, Shonna Johnston, Robert Grecian, Azin Poon, Sarah McNamara, Isla Harper, Max Head Fourman, Alejandro J Brenes, Shalini Pathak, Amy Lloyd, Gio Rodriguez Blanco, Alex Von Kriegsheim, Bart Ghesquiere, Wesley Vermaelen, Camilla T Cologna, Kevin Dhaliwal, Nik Hirani, David Dockrell, Moira KB Whyte, David M Griffith, Doreen A Cantrell and Sarah R Walmsley.
medRxiv (18 September 2020) https://doi.org/10.1101/2020.09.15.20195305

‘Genomic network analysis of an environmental and livestock IncF plasmid population’ 

William Matlock, Kevin. K. Chau, Manal AbuOun, Emma Stubberfield, Leanne Barker, James KavanaghHayleah PickfordDaniel GilsonRichard P. SmithH. Soon GweonSarah J. HoosdallyJeremy SwannRobert SebraMark J. BaileyTimothy E. A. PetoDerrick W. CrookMuna F. AnjumDaniel S. ReadA. Sarah Walker, Nicole Stoesser and Liam P. Shawon behalf of the REHAB consortium. 
bioRxiv (24 July 2020) https://doi.org/10.1101/2020.07.24.215889

‘Differential occupational risks to healthcare workers from SARS-CoV-2: A prospective observational study’
David W. Eyre, Sheila Lumley, Denise O’Donnell, Mark Campbell, Elizabeth Sims, Elaine Lawson, Fiona Warren, Tim J. James, Stuart Cox, Alison Howarth, George Doherty, Stephanie B. Hatch, James Kavanagh, Kevin. K Chau, Philip W. Fowler, Jeremy Swann, Denis Volk, Dan Yang-Turner, Nicole Stoesser and 33 others
medRxiv (29 June 2020) https://doi.org/10.1101/2020.06.24.20135038

‘Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β‐Lactamase from Escherichia coli’
Pauline A. Lang, Anete Parkova, Thomas M. Leissing, Karina Calvopiña, Ricky Cain, Alen Krajnc,  Tharindi D. Panduwawala, Jules Philippe, Colin W. G. Fishwick, Peteris Trapencieris, Malcolm G. P. Page, Christopher J. Schofield and Jürgen Brem
Biomolecules 2020, 10, 899; http://doi:10.3390/biom10060899

‘The Effect of Ageing on the Resolution of Inflammation’
Wezi Sendama 
Ageing Research Reviews 57 (2020) 101000; https://doi.org/10.1016/j.arr.2019.101000

‘Storytelling as a research tool and intervention around public health perceptions and behaviour: a protocol for a systematic narrative review’ 
Becky McCall,  Laura Shallcross, Michael Wilson, Christopher Fuller and Andrew Hayward 
BMJ Open (2019); 9:e030597; https://doi:10.1136/bmjopen-2019-030597

‘Regulation of Apoptotic Cell Clearance During Resolution of Inflammation’
Simone Arienti, N.D. Barth, D.A. Dorwood, A.G. Rossi and I. Dransfield
Front. Pharmacol (2019): 10:891; https://doi:10.3389/fphar.2019.00891

‘The Impact of Hypoxia on the Host-Pathogen Interaction between Neutrophils and Staphylococcus aureus
Natalia H. Hajdamowicz, Rebecca C. Hull, Simon J. Foster and Alison M. Condliffe 

Int. J. Mol. Sci. (2019) 20, 5561; https://doi:10.3390/ijms20225561

‘Will Morphing Boron-Based Inhibitors Beat the β-lactamases?’

Alen Krajnc*, Pauline A. Lang*, Tharindi D. Panduwawala*, Jürgen Brem* and Christopher J. Schofield* (*authors contributed equally). 
Current Opinion in Chemical Biology (2019) 50; https://doi.org/10.1016/j.cbpa.2019.03.001

‘Targeting the Mycobacterium tuberculosis Transpeptidase LdtMt2 with Cysteine-Reactive Inhibitors including Ebselen’
Mariska de Munnik, Christopher T. Lohans, Pauline A. Lang, Gareth W. Langley, Tika R. Malla, Anthony Tumber, Christopher J. Schofield and Jürgen Brem. 
Chem. Commun. (2019) 55, 69; https://doi.org/10.1039/C9CC04145A 

‘Molecular Basis of Class A β-lactamase Inhibition by Relebactam’
Catherine L. Tooke, Philip Hinchliffe, Pauline A. Lang, Adrian J. Mulholland, Jürgen Brem, Christopher J. Schofield and James Spencer.  
Antimicrobial Agents and Chemotherapy (2019); https://doi.org/10.1128/AAC.00564-19

‘Mapping the Hydrophobic Substrate Binding Site of Phenylalanine Ammonia Lyase from Petroselinum crispum’
Emma Zsófia Aletta Nagy, Diana Souad Tork, Pauline A. Lang, Alina Filip, Florin Dan Irimie,  László Poppe et al.
ACS Catalysis. (2019); https://doi.org/10.1021/acscatal.9b02108